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ºÙºÙÊÓƵ Provider

Un J. Kang, MD

ºÙºÙÊÓƵ Provider
  • Specialty: Parkinson's & Movement Disorders
  • Treats: Adults
  • Language: English
  • Phone: 212-263-4838
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I have always been fascinated by how our brains allow us to think, move, and experience the world, and how these seemingly universal abilities can be significantly impacted by neurological disorders. My interests led me to receive training in both the clinical skills for diagnosis and management of movement disorders and in basic experimental science to address how normal function is disrupted in these disorders.

As a physician–scientist at ºÙºÙÊÓƵ, I provide care for people who have Parkinson’s disease and related movement disorders, including tremor, tics, dystonia, and Huntington’s disease, using the best available treatments. I am the director of translational research at the Fresco Institute for Parkinson’s and Movement Disorders, where I strive to learn more about how disease affects patients in their daily lives on an individual level.

I apply basic science knowledge and clinical bedside experience to researching the underlying mechanisms of disease at the . These insights help our team to understand what each patient experiences and how therapies can be formulated to fit individual needs.

I also co-direct the , where we try to discover common pathogenic mechanisms underlying seemingly different neurological disorders and foster collaborative research involving basic science and clinical medicine.

Before joining ºÙºÙÊÓƵ in 2019, I created and led a multidisciplinary team of basic researchers and clinical experts in movement disorders at the University of Chicago for two decades. More recently, I was the chief of the division of movement disorders in the Department of Neurology at Columbia University.


Conditions and Treatments

Conditions
  • abnormal gait
  • ataxia
  • chorea
  • dystonia
  • essential tremor
  • Fahr's syndrome
  • fragile X-associated tremor/ataxia syndrome (FXTAS)
  • huntington's disease
  • idiopathic torsion dystonia
  • involuntary muscle jerking
  • lewy body dementia
  • meige syndrome
  • movement disorders
  • multiple system atrophy
  • olivopontocerebellar degeneration
  • opsoclonus myoclonus ataxia syndrome (OMAS)
  • painful leg and moving toes syndrome
  • parkinson's disease
  • progressive supranuclear palsy
  • rem sleep behavior disorder
  • restless leg syndrome
  • shy-drager syndrome
  • spasmodic dysphonia
  • spasmodic torticollis
  • spinocerebellar ataxia
  • stereotypic movement disorder
  • striato-nigral degeneration
  • tardive dyskinesia
  • tic disorder
  • tourette disorder
  • tremor (any type)

Positions
  • Founders Professor of Neurology,
  • Professor,
  • Director, Translational Research Dept of Neurology
Board Certifications
  • American Board of Psychiatry & Neurology - Neurology, 1987
Education and Training
  • Fellowship, NY Presbyterian - Columbia University Medical Center, Movement Disorders, 1987
  • Residency, NY Presbyterian - Columbia University Medical Center, Neurology, 1986
  • MD from Johns Hopkins University, 1982

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Un J. Kang, MD does not accept insurance.

Locations and Appointments

Video Visits

See a doctor from your mobile device instead of an in-person appointment. .

Schedule a Video Visit
Fresco Institute for Parkinson's & Movement Disorders

222 East 41st Street, 13th Floor, New York, NY 10017

Phone

212-263-4838

Fax

212-263-4837

Schedule Appointment

Interests

Parkinson's disease, movement disorders, basal ganglia circuit, neural plasticity, catecholamine, biomarkers

Research Summary

My research is a part of multidisciplinary effort by a team of basic and clinical scientists to understand the mechanisms underlying Parkinson’s disease (PD) and related movement disorders.  I pioneered experimental gene therapy approaches to replace dopamine for PD.  My laboratory research now focuses on understanding how brain circuitry is perturbed by the dopamine loss and by pharmacological treatment in mouse models of PD.  We hope to understand the circuit mechanisms of exercise, rehabilitation, medication, and surgical intervention in PD.  We are also exploring circuitry mechanisms underlying gait and freezing and non-motor symptoms of PD that have not been adequately addressed by the current therapies. 

In addition, we are interested in the molecular dysfunctions that contribute to neuronal degeneration in PD, multiple system atrophy (MSA), and related neurodegenerative disorders and translating this knowledge develop biomarkers that can help us to predict, diagnose, prognosticate, monitor progression and understand heterogeneity of the disease better. These tools may allow us to improve our individualized care of patients and facilitate the development of new therapies.

 

Academic Contact

Academic office

435 E 30th Street, Science Building

10th floor, 1013

New York, NY 10016

Lab Website

  • Prodromal and Early Parkinsonism Alpha-Synuclein Study

  • THE NEW YORK MOVEMENT DISORDER STUDY

  • EARLY DETECTION OF ALPHA-SYNUCLEIN DISEASE Single-center cross-sectional and longitudinal non-interventional observational study of biomarkers in prodromal synucleinopathy

  • Cheung, Timothy H C; Ding, Yunmin; Zhuang, Xiaoxi; Kang, Un Jung

    Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2023 Mar 21; 120(12):e2213093120

  • Russo, Marco J; Orru, Christina D; Concha-Marambio, Luis; Giaisi, Simone; Groveman, Bradley R; Farris, Carly M; Holguin, Bret; Hughson, Andrew G; LaFontant, David-Erick; Caspell-Garcia, Chelsea; Coffey, Christopher S; Mollon, Jennifer; Hutten, Samantha J; Merchant, Kalpana; Heym, Roland G; Soto, Claudio; Caughey, Byron; Kang, Un Jung

    Acta neuropathologica communications. 2021 11 06; 9(1):179

  • Choi, Se Joon; Ma, Thong C; Ding, Yunmin; Cheung, Timothy; Joshi, Neal; Sulzer, David; Mosharov, Eugene V; Kang, Un Jung

    eLife. 2020 Jul 20; 9:

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